![]() In immunology, cell types have been historically recognized and well characterized. Technological advances in single-cell and spatial genomics are rapidly expanding the compendium of known cell types 3 and accelerating discoveries of a large variety of novel cell populations.įor instance, these efforts have been applied to system-level disciplines such as immunology and neuroscience, both of which require an understanding of vast networks of cells and tissues. With collaborations of over 2,000 scientists across more than 1,000 institutes from 76 countries to date, the Human Cell Atlas (HCA) has generated comprehensive molecular profiles of tens of millions of single cells across 18 different organs and systems, which in turn are advancing our understanding of the definition of cell types and states 1, 2.
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